Consortium Publications
- The role of neurotrophic factors in novel, rapid psychiatric treatments
Kim JH, He MJ, Widmann AK, Lee FS
Neuropsychopharmacology. 2024; 49(1):227-245. - Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk
Lao-Peregrin C, Xiang GQ, Kim JH, Srivastava I, Fall AB, Gerhard DM, Kohtala P, Kim DG, Song MS, Garcia-Marcos M, Levitz J, Lee FS
Cell Rep. 2024; 43(1):113595. - The why, when, where, how, and so what of so-called rapidly acting antidepressants
Schatzberg AF, Mathew SJ
Neuropsychopharmacology. 2024; 49(1):189-196. - Cell-Type Specific Reductions in Interneuron Gene Expression within Subregions of the Anterior and Posterior Cingulate Gyrus of Schizophrenia and Bipolar Disorder Subjects
Krolewski DM, Waselus M, Bunney BG, Myers RM, Barchas JD, Lee FS, Schatzberg AF, Bunney WE, Akil H, Watson SJ
bioRxiv. 2024. - Allele biased transcription factor binding across human brain regions gives mechanistic insight into eQTLs
Moyers BA, Loupe JM, Felker SA, Lawlor JMJ, Anderson AG, Rodriguez-Nunez I, Bunney WE, Bunney BG, Cartagena PM, Sequeira A, Watson SJ, Akil H, Mendenhall EM, Cooper GM, Myers RM
bioRxiv. 2023. - Regulation of social interaction in mice by a frontostriatal circuit modulated by established hierarchical relationships
Fetcho RN, Hall BS, Estrin DJ, Walsh AP, Schuette PJ, Kaminsky J, Singh A, Roshgodal J, Bavley CC, Nadkarni V, Antigua S, Huynh TN, Grosenick L, Carthy C, Komer L, Adhikari A, Lee FS, Rajadhyaksha AM, Liston C
Nat Commun. 2023; 14(1):2487. - Translating developmental neuroscience to understand risk for psychiatric disorders
Meyer HC, Lee FS
Am J Psychiatry. 2023; 180(8):540-547. - Intermixed safety cues facilitate extinction retention in adult and adolescent mice
Meyer HC, Lee FS
Physiol Behav. 2023; 271:114336. - Toward a Precision Treatment Approach for Metabolic Depression: Integrating Epidemiology, Neuroscience, and Psychiatry
Watson K, Akil H, Rasgon N
Biol Psychiatry Glob Open Sci. 2023; 3(4):623-631. - The temporal structure of REM sleep shows minute-scale fluctuations across brain and body in mice and humans
Bueno-Junior LS, Ruckstuhl MS, Lim MM, Watson BO
Proc Natl Acad Sci USA. 2023; 120(18):e221343812. - High emotional reactivity is associated with activation of a molecularly distinct hippocampal-amygdala circuit modulated by the glucocorticoid receptor
Wei Q, Kumar V, Moore S, Li F, Murphy GG, Watson SJ, Akil H
Neurobiol Stress. 2023; 27:100581. - The impact of COVID-19 on a college freshman sample reveals genetic and nongenetic forms of susceptibility and resilience to stress
Turner CA, Khalil H, Murphy-Weinberg V, Hagenauer MH, Gates L, Tang Y, Weinberg L, Grysko R, Floran-Garduno L, Dokas T, Samaniego C, Zhao Zhuo, Fang Y, Sen S, Lopez JF, Watson SJ, Akil H
Proc Natl Acad Sci USA. 2023; 120(49):e2305779120. - Neurotransmission-related gene expression in the frontal pole is altered in subjects with bipolar disorder and schizophrenia
Medina AM, Hagenauer MH, Krolewski DM, Hughes E, Forrester LC, Walsh DM, Waselus M, Richardson E, Turner CA, Sequeira PA, Cartagena PM, Thompson RC, Vawter MP, Bunney BG, Myers RM, Barchas JD, Lee FS, Schatzberg AF, Bunney WE, Akil H, Watson SJ
Transl Psychiatry. 2023; 13(1):118. - Ecological validity of social defeat stressors in mouse models of vulnerability and resilience
Lyons DM, Ayash S, Schatzberg AF, Müller MB
Neurosci Biobehav Rev. 2023; 145:105032. - Large Common Mitochondrial DNA Deletions Are Associated with a Mitochondrial SNP T14798C Near the 3' Breakpoints
Hjelm BE, Ramiro C, Rollins BL, Omidsalar AA, Gerke DS, Das SC, Sequeira A, Morgan L, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Bunnery WE, Vawter MP
Complex Psychiatry. 2023; 8(3-4):90-98. - Blood-based biomarkers for suicide in depression: moving a step closer to prediction
Mamdani F, Sequeira A
Neuropsychopharmacology. 2023; 48:245-246. - Control of Gαq signaling dynamics and GPCR cross-talk by GRKs
Xiang G, Acosta-Ruiz A, Radoux-Mergault A, Kristt M, Kim J, Moon JD, Broichhagen J, Inoue A, Lee FS, Stoeber M, Dittman JS, Levitz J
Sci Adv. 2022; 8(47):eabq3363. - Forebrain glucocorticoid receptor overexpression alters behavioral encoding of hippocampal CA1 pyramidal cells in mice
Gavade S, Wei Q, Johnston C, Kounelis-Wuillaume S, Laborc K, Baranwal S, Akil H, Spencer-Segal JL
eNeuro. 2022; 9(6):ENEURO.0126-22. - Overexpression of cancer- and neurotransmitter-associated genes in the nucleus accumbens of smokers
Stein R, Mamdani F, Bunney B, Cartagena P, Vawter MP, Schatzberg AF, Barchas J, Lee FS, Myers R, Watson SJ, Akil H, Bunney WE, Sequeira A
Epub ahead of print. 2022. - Regional gene expression signatures are associated with sex-specific functional connectivity changes in depression
Talishinsky A, Downar J, Vértes PE, Seidlitz J, Dunlop K, Lynch CJ, Whalley H, McIntosh A, Vila-Rodriguez F, Daskalakis ZJ, Blumberger DM, Liston C
Nat Commun. 2022; 13(1):5692. - Neurotransmission-related gene expression in the frontal pole (Brodmann Area 10) is altered in subjects with bipolar disorder and schizophrenia
Medina AM, Hagenauer MH, Krolewski DM, Hughes E, Forrester LCT, Walsh DM, Waselus M, Richardson E, Turner CA, Sequiera PA, Preston Cartagena P, Thompson RC, Vawter MP, Bunney BG, Myers RM, Barchas JD, Lee, FSY, Schatzberg AF, Bunney WE, Huda Akil A, Watson SJ
Transl Psychiatry. 2022; Epub ahead of print. - Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder
Das SC, Hjelm BE, Rollins BL, Sequeira A, Morgan L, Omidsalar AA, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP
Transl Psychiatry. 2022; 12(1):353. - Rare coding variants in ten genes confer substantial risk for schizophrenia
Singh T, Poterba T, Curtis D, Akil H, Al Eissa M, Barchas JD, Bass N, Bigdeli TB, Breen G, Bromet EJ, Buckley PF, Bunney WE, Bybjerg-Grauholm J, Byerley WF, Chapman SB, Chen WJ, Churchhouse C, Craddock N, Cusick CM, DeLisi L, Dodge S, Escamilla MA, Eskelinen S, Fanous AH, Faraone SV, Fiorentino A, Francioli L, Gabriel SB, Gage D, Gagliano Taliun SA, Ganna A, Genovese G, Glahn DC, Grove J, Hall MH, Hämäläinen E, Heyne HO, Holi M, Hougaard DM, Howrigan DP, Huang H, Hwu HG, Kahn RS, Kang HM, Karczewski KJ, Kirov G, Knowles JA, Lee FS, Lehrer DS, Lescai F, Malaspina D, Marder SR, McCarroll SA, McIntosh AM, Medeiros H, Milani L, Morley CP, Morris DW, Mortensen PB, Myers RM, Nordentoft M, O'Brien NL, Olivares AM, Ongur D, Ouwehand WH, Palmer DS, Paunio T, Quested D, Rapaport MH, Rees E, Rollins B, Satterstrom FK, Schatzberg A, Scolnick E, Scott LJ, Sharp SI, Sklar P, Smoller JW, Sobell JL, Solomonson M, Stahl EA, Stevens CR, Suvisaari J, Tiao G, Watson SJ, Watts NA, Blackwood DH, Børglum AD, Cohen BM, Corvin AP, Esko T, Freimer NB, Glatt SJ, Hultman CM, McQuillin A, Palotie A, Pato CN, Pato MT, Pulver AE, St Clair D, Tsuang MT, Vawter MP, Walters JT, Werge TM, Ophoff RA, Sullivan PF, Owen MJ, Boehnke M, O'Donovan MC, Neale BM, Daly MJ
Nature. 2022; 604(7906):509-516. - Identification of potential blood biomarkers associated with suicide in major depressive disorder
Mamdani F, Weber MD, Bunney B, Burke K, Cartagena P, Walsh D, Lee FS, Barchas J, Schatzberg AF, Myers RM, Watson SJ, Akil H, Vawter MP, Bunney WE, Sequeira A
Transl Psychiatry. 2022; 12(1):159. - Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model
Maras PM, Hebda-Bauer EK, Hagenauer MH, Hilde KL, Blandino P Jr, Watson SJ Jr, Akil H
Transl Psychiatry. 2022; 12(1):105. - Characterizing the behavioral and neuroendocrine features of susceptibility and resilience to social stress
Murra D, Hilde KL, Fitzpatrick A, Maras PM, Watson SJ, Akil H
Neurobiol Stress. 2022; 17:100437. - Long-term effects of intermittent early life stress on primate prefrontal-subcortical functional connectivity
Yuan R, Nechvatal JM, Buckmaster CL, Ayash S, Parker KJ, Schatzberg AF, Lyons DM, Menon V
Neuropsychopharmacology. 2021; 46(7):1348-1356. - Accelerated brain aging predicts impulsivity and symptom severity in depression
Dunlop K, Victoria LW, Downar J, Gunning FM, Liston C
Neuropsychopharmacology. 2021; 46(5):911-919. - Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics
Buch AM, Liston C
Neuropsychopharmacology. 2021; 46(1):156-175. - Prefrontal deep projection neurons enable cognitive flexibility via persistent feedback monitoring
Spellman T, Svei M, Kaminsky J, Manzano-Nieves G, Liston C
Cell. 2021; 184(10):2750-2766.e17. - Role of BDNF in the development of an OFC-amygdala circuit regulating sociability in mouse and human
Li A, Jing D, Dellarco DV, Hall BS, Yang R, Heilberg RT, Huang C, Liston C, Casey BJ, Lee FS
Mol Psychiatry. 2021; 26(3):955-973. - Pre-adolescent stress disrupts adult, but not adolescent, safety learning
Meyer HC, Gerhard DM, Amelio PA, Lee FS
Behav Brain Res. 2021; 400:113005. - Optimization and evaluation of fluorescence in situ hybridization chain reaction in cleared fresh-frozen brain tissues
Kumar V, Krolewski DM, Hebda-Bauer EK, Parsegian A, Martin B, Foltz M, Akil H, Watson SJ
Brain Struct Funct. 2021; 226(2):481-499. - Repeated Dosing of Ketamine in the Forced Swim Test: Are Multiple Shots Better Than One?
Weston RG, Fitzgerald PJ, Watson BO
Front Psychiatry. 2021; 12:659052. - Multiple cholinesterase inhibitors have antidepressant-like properties in the mouse forced swim test
Fitzgerald PJ, Hale PH, Ghimire A, Watson BO
Behav Brain Res. 2021; 409:113323. - Incident Major Depressive Disorder Predicted by Three Measures of Insulin Resistance: A Dutch Cohort Study
Watson KT, Simard JF, Henderson VW, Nutkiewicz L, Lamers F, Nasca C, Rasgon N, Penninx BWJH
Am J Psychiatry. 2021; 178(10):914-920. - An adolescent sensitive period for threat responding: impacts of stress and sex
Gerhard DM, Meyer HC, Lee FS
Biol Psychiatry. 2021; 89(7):651-658. - Accelerated brain aging predicts impulsivity and symptom severity in depression
Dunlop K, Victoria LW, Downar J, Gunning FM, Liston C
Neuropsychopharmacology. 2021; 46(5):911-919. - Role of BDNF in the development of an OFC-amygdala circuit regulating sociability in mouse and human
Li A, Jing DQ, Dellarco DV, Hall BS, Yang R, Heilberg RT, Huang C, Liston C, Casey BJ, Lee FS
Mol Psychiatry. 2021; 26(3):955-973. - Optimization and evaluation of fluorescence in situ hybridization chain reaction in cleared fresh-frozen brain tissues
Kumar V, Krolewski DM, Hebda-Bauer EK, Parsegian A, Martin B, Foltz M, Akil H, Watson SJ Jr
Brain Struct Funct. 2021; 226(2):481-499. - Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model
Birt IA, Hagenauer MH, Clinton SM, Aydin C, Blandino P Jr, Stead JDH, Hilde KL, Meng F, Thompson RC, Khalil H, Stefanov A, Maras P, Zhou Z, Hebda-Bauer EK, Goldman D, Watson SJ Jr, Akil H
Biol Psychiatry. 2021; 89(4):339-355. - Long-term effects of intermittent early life stress on primate prefrontal-subcortical functional connectivity
Yuan R, Nechvatal JM, Buckmaster CL, Ayash S, Parker KJ, Schatzberg AF, Lyons DM, Menon V
Neuropsychopharmacology. 2021; Online ahead of print. - Prefrontal deep projection neurons enable cognitive flexibility via persistent feedback monitoring
Spellman T, Svei M, Kaminsky J, Manzano-Nieves G, Liston C
Biorxiv. 2021; Online ahead of print. - Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics
Buch A, Liston C
Neuropsychopharmacology. 2021; 46(1):156-175. - The cholinesterase inhibitor donepezil has antidepressant-like properties in the mouse forced swim test
Fitzgerald PJ, Hale PJ, Ghimire A, Watson BO
Transl Psychiatry. 2020; 10(1):255. - The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
Coleman JRI, Gaspar HA, Bryois J
Biol Psychiatry. 2020; 88(2):169-184. - Endogenous Opioids at the Intersection of Opioid Addiction, Pain, and Depression: The Search for a Precision Medicine Approach
Emery MA, Akil H
Annu Rev Neurosci. 2020; 43:355-374. - Causes and Consequences of Diagnostic Heterogeneity in Depression: Paths to Discovering Novel Biological Depression Subtypes
Lynch CJ, Liston C
Biol Psychiatry. 2020; 88(1):83-94. - Sepsis survivor mice exhibit a behavioral endocrine syndrome with ventral hippocampal dysfunction
Spencer-Segal JL, Singer BH, Laborc K, Somayaji K, Watson SJ, Standiford TJ, Akil H
Psychoneuroendocrinology. 2020; 117:104679. - Toward Circuit Mechanisms of Pathophysiology in Depression
Spellman T, Liston C
Am J Psychiatry. 2020; 177(5):381-390. - Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice
Burgdorf CE, Jing DQ, Yang R, Huang C, Hill MN, Mackie K, Milner TA, Pickel VM, Lee FS, Rajadhyaksha AM
Sci Adv. 2020; 6(7):eaay1502. - Blockade of the cholecystokinin CCK-2 receptor prevents the normalization of anxiety levels in the rat
Ballaz SJ, Bourin M, Akil H, Watson SJ
Prog Neuropsychopharmacol Biol Psychiatry. 2020; 97:109761. - Revisiting the stress concept: Implications for affective disorders
McEwen BS, Akil H
J Neurosci. 2020; 40(1):12-21. - Multisensory modulation of body ownership in mice
Buckmaster CL, Rathmann-Bloch JE, de Lecea L, Schatzberg AF, Lyons DM
Neurosci Conscious. 2020; 2020(1):niz019. - Ventral hippocampus interacts with prelimbic cortex during inhibition of threat response via learned safety in both mice and humans
Meyer HC, Odriozola P, Cohodes EM, Mandell JD, Li A, Yang R, Hall BS, Haberman JT, Zacharek SJ, Liston C, Lee FS, Gee DG
Proc Natl Acad Sci U S A. 2019:pii: 201910481. - HPA axis in psychotic major depression and schizophrenia spectrum disorders: Cortisol, clinical symptomatology, and cognition
Cherian K, Schatzberg AF, Keller J
Schizophr Res. 2019; 213:72-79. - Association of myoinositol transporters with schizophrenia and bipolar disorder: Evidence from human and animal studies
Vawter MP, Hamzeh AR, Muradyan E, Civelli O, Abbott GW, Alachkar A
Mol Neuropsychiatry. 2019; 5(4):200-211. - Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABAA receptors
Limon A, Delbruck E, Yassine A, Pandya D, Myers RM, Barchas JD, Lee F, Schatzberg, Watson SJ, Akil H, Bunney WE, Vawter MP, Sequeira A
Transl Psychiatry. 2019; 9(1):218. - Adaptation to single housing is dynamic: Changes in hormone levels, gene expression, signaling in the brain, and anxiety-like behavior in adult male C57Bl/6J mice
Hebda-Bauer EK, Dokas LA, Watson SJ, Akil H
Horm Behav. 2019; 114:104541. - Effects of early-life FGF2 on ultrasonic vocalizations (USVs) and the mu-opioid receptor in male Sprague-Dawley rats selectively-bred for differences in their response to novelty
Turner CA, Hagenauer MH, Aurbach EL, Maras PM, Fournier CL, Blandino P, Chauhan RB, Panksepp J, Watson SJ, Akil H
Brain Res. 2019; 1715:106-114. - Modeling the daily rhythm of human pain processing in the dorsal horn
Crodelle J, Pilz S, Hagenauer MH, Booth V
PLoS Comput Biol. 2019; 15(7):e1007106. - Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders
Hjelm BE, Rollins B, Morgan L, Sequeira A, Mamdani F, Pereira F, Damas J, Webb MG, Weber MD, Schatzberg AF, Barchas JD, Lee FS, Akil H, Watson SJ, Myers RM, Chao EC, Kimonis V, Thompson PM, Bunney WE, Vawter MP
Nucleic Acids Res. 2019; 47(10):e59. - Genome-wide association study identifies 30 loci associated with bipolar disorder
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, Bækvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, Bøen E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvsåshagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Frisén L, Gade K, Gage D, Garnham J, Giambartolomei C, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS, Juréus A, Kandaswamy R, Karlsson R, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koller AC, Kupka R, Lavebratt C, Lawrence J, Lawson WB, Leber M, Lee PH, Levy SE, Li JZ, Liu C, Lucae S, Maaser A, MacIntyre DJ, Mahon PB, Maier W, Martinsson L, McCarroll S, McGuffin P, McInnis MG, McKay JD, Medeiros H, Medland SE, Meng F, Milani L, Montgomery GW, Morris DW, Mühleisen TW, Mullins N, Nguyen H, Nievergelt CM, Adolfsson AN, Nwulia EA, O'Donovan C, Loohuis LMO, Ori APS, Oruc L, Ösby U, Perlis RH, Perry A, Pfennig A, Potash JB, Purcell SM, Regeer EJ, Reif A, Reinbold CS, Rice JP, Rivas F, Rivera M, Roussos P, Ruderfer DM, Ryu E, Sánchez-Mora C, Schatzberg AF, Scheftner WA, Schork NJ, Shannon Weickert C, Shehktman T, Shilling PD, Sigurdsson E, Slaney C, Smeland OB, Sobell JL, Søholm Hansen C, Spijker AT, St Clair D, Steffens M, Strauss JS, Streit F, Strohmaier J, Szelinger S, Thompson RC, Thorgeirsson TE, Treutlein J, Vedder H, Wang W, Watson SJ, Weickert TW, Witt SH, Xi S, Xu W, Young AH, Zandi P, Zhang P, Zöllner S; eQTLGen Consortium; BIOS Consortium, Adolfsson R, Agartz I, Alda M, Backlund L, Baune BT, Bellivier F, Berrettini WH, Biernacka JM, Blackwood DHR, Boehnke M, Børglum AD, Corvin A, Craddock N, Daly MJ, Dannlowski U, Esko T, Etain B, Frye M, Fullerton JM, Gershon ES, Gill M, Goes F, Grigoroiu-Serbanescu M, Hauser J, Hougaard DM, Hultman CM, Jones I, Jones LA, Kahn RS, Kirov G, Landén M, Leboyer M, Lewis CM, Li QS, Lissowska J, Martin NG, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Metspalu A, Mitchell PB, Morken G, Mors O, Mortensen PB, Müller-Myhsok B, Myers RM, Neale BM, Nimgaonkar V, Nordentoft M, Nöthen MM, O'Donovan MC, Oedegaard KJ, Owen MJ, Paciga SA, Pato C, Pato MT, Posthuma D, Ramos-Quiroga JA, Ribasés M, Rietschel M, Rouleau GA, Schalling M, Schofield PR, Schulze TG, Serretti A, Smoller JW, Stefansson H, Stefansson K, Stordal E, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Werge T, Nurnberger JI, Wray NR, Di Florio A, Edenberg HJ, Cichon S, Ophoff RA, Scott LJ, Andreassen OA, Kelsoe J, Sklar P; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium
Nat Genet. 2019; 51(5):793-803. - Glucocorticoids and resilience
Spencer-Segal JL, Akil H
Horm Behav. 2019; 111:131-134. - Role of BDNF in the development of an OFC-amygdala circuit regulating sociability in mouse and human
Li A, Jing D, Dellarco DV, Hall BS, Yang R, Heilberg RT, Huang C, Liston C, Casey BJ, Lee FS
Mol Psychiatry. 2019. - Translating developmental neuroscience to understand risk for psychiatric sisorders
Meyer HC, Lee FS
Am J Psychiatry. 2019; 176(3):179-185. - Novel complex interactions between mitochondrial and nuclear DNA in schizophrenia and bipolar disorder
Schulmann A, Ryu E, Goncalves V, Rollins B, Christiansen M, Frye MA, Biernacka J, Vawter MP
Mol Neuropsychiatry. 2019; 5(1):13-27. - Neural cell adhesion molecule peptide mimetics modulate emotionality: pharmacokinetic and behavioral studies in rats and non-human primates
Turner CA, Lyons DM, Buckmaster CL, Aurbach EL, Watson SJ Jr, Schatzberg AF, Akil H
Neuropsychopharmacology. 2019; 44(2):356-363. - Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium
Cell. 2018; 173(7):1705-1715. - Learning to actively cope with stress in female mice
Lyons DM, Buckmaster CL, Schatzberg AF
Psychoneuroendocrinology. 2018; 96:78-83. - Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism
Williams NR, Heifets BD, Blasey C, Sudheimer K, Pannu J, Pankow H, Hawkins J, Birnbaum J, Lyons DM, Rodriguez CI, Schatzberg AF
Am J Psychiatry. 2018; appiajp201818020138. - Fibroblast growth factor 2 regulates activity and gene expression of human post-mitotic excitatory neurons
Gupta S, M-Redmond T, Meng F, Tidball A, Akil H, Watson S, Parent JM, Uhler M
J Neurochem. 2018; 145(3):188-203. - Uneven balance of power between hypothalamic peptidergic neurons in the control of feeding
Wei Q, Krolewski DM, Moore S, Kumar V, Li F, Martin B, Tomer R, Murphy GG, Deisseroth K, Watson SJ Jr, Akil H
Proc Natl Acad Sci U S A. 2018; 115(40):E9489-E9498. - Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis
Hagenauer MH, Schulmann A, Li JZ, Vawter MP, Walsh DM, Thompson RC, Turner CA, Bunney WE, Myers RM, Barchas JD, Schatzberg AF, Watson SJ Jr, Akil H
PLoS One. 2018; 13(7):e0200003. - Connective tissue growth factor Is a novel prodepressant
Turner CA, Sharma V, Hagenauer MH, Chaudhury S, O'Connor AM, Hebda-Bauer EK, Thompson RC, Myers RM, Bunney WE, Barchas JD, Lee FS, Schatzberg AF, Watson SJ Jr, Akil H
Biol Psychiatry. 2018; 84(8):555-562. - Quantitative validation of immunofluorescence and lectin staining using reduced CLARITY acrylamide formulations
Krolewski DM, Kumar V, Martin B, Tomer R, Deisseroth K, Myers RM, Schatzberg AF, Lee FS, Barchas JD, Bunney WE, Akil H, Watson SJ Jr
Brain Struct Funct. 2018; 223(2):987-999. - The BDNF Val66Met prodomain disassembles dendritic spines altering fear extinction circuitry and behavior
Giza JI, Kim J, Meyer HC, Anastasia A, Dincheva I, Zheng CI, Lopez K, Bains H, Yang J, Bracken C, Liston C, Jing DQ, Hempstead BL, Lee FS
Neuron. 2018; 99:163-178. - Acetyl-l-carnitine deficiency in patients with major depressive disorder
Nasca C, Bigio B, Lee FS, Young SP, Kautz MM, Albright A, Beasley J, Millington DS6, Mathé AA, Kocsis JH, Murrough JW, McEwen BS, Rasgon N
Proc Natl Acad Sci U S A. 2018; 115(34):8627-8632. - Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance
Balsevich G, Sticht M, Bowles NP, Singh A, Lee TT, Li Z, Chelikani PK, Lee FS, Borgland SL, Hillard CJ, McEwen BS, Hill MN
Proc Natl Acad Sci U S A. 2018; 115(29):7605-7610. - Translational profiling of stress-induced neuroplasticity in the CA3 pyramidal neurons of BDNF Val66Met mice
Gray JD, Rubin TG, Kogan JF, Marrocco J, Weidmann J, Lindkvist S, Lee FS, Schmidt EF, McEwen BS
Mol Psychiatry. 2018; 23(4):904-913. - Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence
Rollins BL, Morgan L, Hjelm BE, Sequeira A, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP
Mol Neuropsychiatry. 2018; 3(3):157-169. - Corticotropin-releasing factor 1 receptor haplotype and cognitive features of major depression
Davis EG, Keller J, Hallmayer J, Pankow HR, Murphy GM Jr., Gotlib IH, Schatzberg AF
Transl Psychiatry. 2018; 8(1):5. - Combined Analysis of Mifepristone for Psychotic Depression: Plasma Levels Associated With Clinical Response
Block TS, Kushner H, Kalin N, Nelson C, Belanoff J, Schatzberg A
Biol Psychiatry. 2018; pii: S0006-3223(18):30035-0. - The Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development
Meyer HC, Lee FS, Gee DG
Neuropsychopharmacology. 2018; 43(1):21-33. - Utilizing a unique animal model to better understand human temperament
Turner CA, Flagel SB, Blandino P Jr, Watson SJ Jr, Akil H
Curr Opin Behav Sci. 2017; 14:108-114. - Stress amplifies sex differences in primate prefrontal profiles of gene expression
Lee AG, Hagenauer M, Absher D, Morrison KE, Bale TL, Myers RM, Watson SJ, Akil H, Schatzberg AF, Lyons DM
Biol Sex Differ. 2017; 8(1):36. - Blockade of alcohol escalation and "relapse" drinking by pharmacological FAAH inhibition in male and female C57BL/6J mice
Zhou Y, Schwartz BI, Giza J, Gross SS, Lee FS, Kreek MJ
Psychopharmacology (Berl). 2017; 234(19):2955-70. - Effect of Early-Life Fluoxetine on Anxiety-Like Behaviors in BDNF Val66Met Mice
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Genome Med. 2017; 9(1):72. - Rare Synaptogenesis-Impairing Mutations in SLITRK5 Are Associated with Obsessive Compulsive Disorder
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Biol Psychiatry. 2016; 80(6):419-21. - Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders
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Microarrays (Basel). 2016; 5(1). - Fibroblast growth factor 2 alters the oxytocin receptor in a developmental model of anxiety-like behavior in male rat pups
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Curr Opin Neurobiol. 2016; 36:112-117. - Common Polymorphisms in the Age of Research Domain Criteria (RDoC): Integration and Translation
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Biol Psychiatry. 2016; 79(1):25-31. - Evidence for alterations of the glial syncytial function in major depressive disorder
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Proc Natl Acad Sci U S A. 2015; 112(38):11953-8. - Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder
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Transl Psychiatry. 2015; 5:e636. - Development of New Psychopharmacological Agents for Depression and Anxiety
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Psychiatr Clin North Am. 2015; 38(3):379-93. - Slitrk5 Mediates BDNF-Dependent TrkB Receptor Trafficking and Signaling
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Dev Cell. 2015; 33(6):690-702. - Treating the Developing versus Developed Brain: Translating Preclinical Mouse and Human Studies
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Neuron. 2015; 86(6):1358-68. - Mitochondrial mutations in subjects with psychiatric disorders
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Mol Psychiatry. 2015; 20(1):48-55. - Anna-Monika Award Lecture, DGPPN Kongress, 2013: the role of the hypothalamic-pituitary-adrenal (HPA) axis in the pathogenesis of psychotic major depression
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World J Biol Psychiatry. 2015; 16(1):2-11. - Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders?
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Neuropsychopharmacology. 2015; 40(2):259-67. - ABCB1 (MDR1) predicts remission on P-gp substrates in chronic depression
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Sci Rep. 2014; 4:5152. - A prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group
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Proc Natl Acad Sci U S A. 2014; 111(17):6131-8. - Altered choroid plexus gene expression in major depressive disorder
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Front Hum Neurosci. 2014; 8:238. - Basal microRNA expression patterns in reward circuitry of selectively bred high-responder and low-responder rats vary by brain region and genotype
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Physiol Genomics. 2014; 46(8):290-301. - Plasma oxytocin concentrations are lower in depressed vs. healthy control women and are independent of cortisol
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Neuroscience. 2013; 248C:571-584. - Interaction between cholecystokinin and the fibroblast growth factor system in the ventral tegmental area of selectively bred high- and low-responder rats
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Neuroscience. 2013; 255:68-75. - G protein-linked signaling pathways in bipolar and major depressive disorders
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Front Genet. 2013; 4:297. - Circadian patterns of gene expression in the human brain and disruption in major depressive disorder
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PNAS. 2013; 110(24):9950-5. - The mineralocorticoid receptor agonist, fludrocortisone, differentially inhibits pituitary-adrenal activity in humans with psychotic major depression
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Psychopharmacology (Berl). 2012; 220(4):731-40. - The melanin-concentrating hormone (MCH) system in an animal model of depression-like behavior
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Biol Psychiatry. 2012; 72(4):254-5. - Treating the developing brain: implications from human imaging and mouse genetics
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Nat Genet. 2011; 43(10):977-83. - A food predictive cue must be attributed with incentive salience for it to induce c-fos mRNA expression in cortico-striatal-thalamic brain regions
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Neuroscience. 2011; 196:80-96. - Pattern of forebrain activation in high novelty-seeking rats following aggressive encounter
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Brain Res. 2011; 1422:20-31. - Impact of the BDNF Val66Met polymorphism on cognition: implications for behavioral genetics
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Neuroscientist. 2011; 18(5):439-51. - Slitrks as emerging candidate genes involved in neuropsychiatric disorders
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Trends Neurosci. 2011; 34(3):143-53. - Selective early-acquired fear memories undergo temporary suppression during adolescence
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PNAS. 2011; 108(3):1182-7. - The first decade and beyond of transcriptional profiling in schizophrenia
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Neurobiol Dis. 2011; 45(1):23-36. - Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population
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Schizophr Res.. 2011; 131(1-3):52-7. - A Retrospective, Edward (Ted) G. Jones, a Neuroscientist and Prolific Neuroanatomist
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PNAS. 2011; 108(43):17597. - Mitochondrial Involvement in Psychiatric Disorders
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Annals of Medicine. 2011; 43(4):329. - Fibroblast growth factor-2 (FGF2) augmentation early in life alters hippocampal development and rescues the anxiety phenotype in vulnerable animals
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Proc Natl Acad Sci U S A. 2011; 108(19):8021-5. - A selective role for dopamine in stimulus-reward learning
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Nature. 2011; 469(7328):53-7. - Short-Hairpin RNA Silencing of Endogenous Fibroblast Growth Factor 2 in Rat Hippocampus Increases Anxiety Behavior
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Biol Psychiatry. 2011; 69(6):534-40. - Challenges and opportunities in mining neuroscience data
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Science. 2011; 331(6018):708-12. - Aberrant Brain Activation During a Working Memory Task in Psychotic Major Depression
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BMC Bioinformatics. 2011; 12(Suppl 1):S36. - Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression
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Molecular Psychiatry. 2011; 16(6):634-46. - Family-based association analysis to finemap bipolar linkage peak on chromosome 8q24 using 2,500 genotyped SNPs and 15,000 imputed SNPs
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Bipolar Disord. 2010; 12(8):786-92. - Presidential address
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Am J Psychiatry. 2010; 167(10):1161-5. - ABCB1 (MDR1) polymorphisms and antidepressant response in geriatric depression
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Pharmacogenet Genomics. 2010; 20(8):467-75. - Identifying gene regulatory networks in schizophrenia
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Psychiatry Res. 2010; 178(2):359-62. - Somatic and neuroendocrine responses to standard and biologically salient acoustic startle stimuli in monkeys
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Psychoneuroendocrinology. 2010; 36(4):547-56. - Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity
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Horm Behav. 2010; 58(3):355-67. - The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus
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J Neurosci. 2010; 30(26):8866-70. - Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons
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Hippocampus. 2010; 21(3):253-64. - Animal models of early life stress: Implications for understanding resilience
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Proc Natl Acad Sci U S A. 2010; 107(33):14823-7. - CRY2 is associated with depression
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PLoS One. 2010; 5(2):e9407. - Expression patterns of corticotropin-releasing factor, arginine vasopressin, histidine decarboxylase, melanin-concentrating hormone, and orexin genes in the human hypothalamus
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Cereb Cortex. 2010; 20(10):2261-4. - Thalamocortical dysrhythmia and chronic pain
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Brain Res Rev. 2010; 66(1-2):83-91. - Forebrain glucocorticoid receptor overexpression increases environmental reactivity and produces a stress-induced spatial discrimination deficit
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Neuroscience. 2010; 169(2):645-53. - Impact of cocaine on adult hippocampal neurogenesis in an animal model of differential propensity to drug abuse
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Eur J Neurosci. 2010; 31(1):79-89. - Variant brain-derived neurotrophic factor Val66Met endophenotypes: implications for posttraumatic stress disorder
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Ann N Y Acad Sci.. 2010; 1208:150-7. - An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction
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Neuropsychopharmacology. 2010; 35(2):388-400. - Failure of anterior cingulate activation and connectivity with the amygdala during implicit regulation of emotional processing in generalized anxiety disorder
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Hum Brain Mapp.. 2010; 31(6):838-51. - Risk-assessment and coping strategies segregate with divergent intrinsic aerobic capacity in rats
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Pharmacol Biochem Behav.. 2010; 92(1):100-4. - GSearcher: Agile Attribute Querying for Biological Networks
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Bioinformatics. 2010; 26(24):3138-3139. - GLay: community structure analysis of biological networks
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BMC Genomics. 2010; 11(Suppl 4):S7. - Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice.
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Nature Medicine. 2010; 16(5):598-603. - Association of a Polyadenylation Polymorphism in the Serotonin Transporter and Panic Disorder
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Biological Psychiatry. 2010; 67(4):331-338. - Analysis of whole genome biomarker expression in blood and brain
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J Psychiatr Res. 2010; 44(2):69-74. - Neural and environmental factors impacting maternal behavior differences in high- versus low- novelty-seeking rats.
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Horm Behav. 2010. - Medicine. The future of psychiatric research: genomes and neural circuits.
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PNAS. 2010; 107:4395-4400. - Cross-Domain Neurobiology Data Integration and Exploration
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BMC Genomics. 2010; 11(s3):s6. - The gputools package enables GPU computing in R
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Bioinformatics. 2010; 26(1):134-135. - Evolutionary sequence modeling for discovery of peptide hormones
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PLoS Computational Biology. 2009; 5(1):e1000258. - Neuropsychological performance as endophenotypes in extended schizophrenia families from the Central Valley of Costa Rica
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Psychiatr Genet. 2009; 19(1):45-52. - Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression
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PLoS One. 2009; 4(8):e6585. - Gender-specific disruptions in emotion processing in younger adults with depression.
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Psychoneuroendocrinology. 2009; 34(7):1012-1018. - Mitochondrial variants in schizophrenia, bipolar disorder, and major depression.
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PLoS One. 2009; 4(3):e4913. - Analyzing gene expression in depression.
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Am J Psychiatry. 2009; 166(9):961-963. - Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation.
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BMC Med Genomics. 2009; 2(62). - A New Role for FGF2 as an Endogenous Inhibitor of Anxiety
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PNAS. 2009; 106:7501-7506. - Integrated Literature and Data Exploration Using Interactive Brain Maps
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Proceedings of BioLink 2009. 2009. - Open Biomedical Ontology-Based Medline Exploration
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BMC Bioinformatics. 2009; 10:Suppl 5: S6. - Gene Expression Profiling of Neurochemically Defined Regions of the Human Brain by In Situ Hybridization-Guided Laser Capture Microdissection
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Novartis Found Symp. 2008; 289:94-100, 193-195. - The acute and post-discontinuation effects of a glucocorticoid receptor (GR) antagonist probe on sleep and the HPA axis in chronic insomnia: a pilot study
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Neuroscience Letters. 2008; 430:147-150. - Psychiatric Genetics: Progress Amid Controversy
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Proceedings of BioLink 2007: Linking Literature, Information and Knowledge for Biology. 2007. - An Active Visual Search Interface for Medline
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Proceedings of the Computational Systems Bioinformatics. 2007:387-390. - Tagging Sentence Boundaries in Biomedical Literature
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BMC Genomics. 2007; 8(336). - Medline Search Engine for Finding Potential Biological Significance of Genetic Markers
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Neuroscience. 2007; 150(2):260-272. - Early life stress and novelty seeking behavior in adolescent monkeys
K. J. Parker; K. L. Rainwater; C. L. Buckmaster; A. F. Schatzberg; S. E. Lindley; D. M. Lyons
Psychoneuroendocrinology. 2007; 32(7):785-792. - Preliminary evidence that hippocampal volumes in monkeys predict stress levels of adrenocorticotropic hormone
T. M. Buckley; B. C. Mullen; A. F. Schatzberg
Biol Psychiatry. 2007; 62(10):1171-1174. - The acute effects of a mineralocorticoid receptor (MR) agonist on nocturnal hypothalamic-adrenal-pituitary (HPA) axis activity in healthy controls
T. M. Buckley; B. C. Mullen; A. F. Schatzberg
Psychoneuroendocrinology. 2007; 32(8-10):859-864. - Rostral Elements of Sympatho-motor Circuitry: A Virally Mediated Transsynaptic Tracing Study
Kerman, Ilan A.; Akil, Huda; Watson, Stanley J.
The Journal of Neuroscience. 2006; 26(13):3423-3433. - SNPs on Chips: The Hidden Genetic Code in Expression Arrays
Sliwerska, Elzbieta; Meng, Fan; Speed, Terence P.; Jones, Edward G.; Bunney, William E.; Akil, Huda; Watson, Stanley J.; Burmeister, Margit
Biological Psychiatry. 2006; 61(1):13-16. - Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders
Vawter, M P; Tomita, H; Meng, F; Bolstad, B; Li, J; Evans, S; Choudary, P; Atz, M; Shao, L; Neal, C; Walsh, D M; Burmeister, M; Speed, T; Myers, R; Jones, E G; Watson, S J; Akil, H; Bunney, W E
Molecular Psychiatry. 2006; 11(7):615, 663-79. - The Fibroblast Growth Factor System and Mood Disorders
Turner, Cortney A.; Akil, Huda; Watson, Stanley J.; Evans, Simon J.
Biological Psychiatry. 2006; 59(12):1128-1135. - Relationship of presympathetic-premotor neurons to the serotonergic transmitter system in the rat brainstem
Kerman, I. A.; Shabrang, C.; Taylor, L.; Akil, H.; Watson, S. J.
Journal of Comparative Neurology. 2006; 499(6):882-896. - Genome scans and gene expression microarrays converge to identify gene regulatory loci relevant in schizophrenia
MP Vawter; ME Atz; BL Rollins; Cooper-Casey KM; L Shao; WF Byerley
Hum Genet. 2006; 119(5):558-70. - Transcriptional profiling of the developing rat brain reveals that the most dramatic regional differentiation in gene expression occurs postpartum.
JD Stead; C Neal; F Meng; Y Wang; S Evans; DM Vazquez; SJ Watson; H Akil
J Neurosci. 2006; 26(1):345-353. - Selective breeding for divergence in novelty-seeking traits: heritability and enrichment in spontaneous anxiety-related behaviors.
JD Stead; S Clinton; C Neal; J Schneider; A Jama; S Miller; DM Vazquez; SJ Watson; H Akil
Behav Genet. 2006; 36(5):697-712. - Social stress-related behavior affects hippocampal cell proliferation in mice
R. Mitra; K. Sundlass; K. J. Parker; A. F. Schatzberg; D. M. Lyons
Physiol Behav. 2006; 89(2):123-127. - Cortisol circadian rhythm alterations in psychotic major depression
J. Keller; B. Flores; R. G. Gomez; H. B. Solvason; H. Kenna; G. H. Williams; A. F. Schatzberg
Biol Psychiatry. 2006; 60(3):275-281. - Combining laser capture microdissection with quantitatitve real-time PCR: effects of tissue manipulation on RNA quality and gene expression.
IA Kerman; BJ Buck; SJ Evans; H Akil; SJ Watson
J Neurosci Methods. 2006; 153(1):71-85. - The neuropsychological profile of psychotic major depression and its relation to cortisol
R. G. Gomez; S. H. Fleming; J. Keller; B. Flores; H. Kenna; C. DeBattista; B. Solvason; A. F. Schatzberg
Biol Psychiatry. 2006; 60(5):472-478. - Maternal mediation, stress inoculation, and the development of neuroendocrine stress resistance in primates
K. J. Parker; C. L. Buckmaster; K. Sundlass; A. F. Schatzberg; D. M. Lyons
Proc Natl Acad Sci U S A. 2006; 103(8):3000-3005. - Application of microarray technology in primate behavioral neuroscience research
A. M. Karssen; J. Z. Li; S. Her; P. D. Patel; F. Meng; S. J. Evans; M. P. Vawter; H. Tomita; P. V. Choudary; W. E. Bunney; Jr. Jones E. G.; S. J. Watson; H. Akil; R. M. Myers; A. F. Schatzberg; D. M. Lyons
Methods. 2006; 38(3):227-234. - Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
Dai, Manhong; Wang, Pinglang; Boyd, Andrew D.; Kostov, Georgi; Athey, Brian; Jones, Edward G.; Bunney, William E.; Myers, Richard M.; Speed, Terry P.; Akil, Huda; Watson, Stanley J.; Meng, Fan
Nucleic Acids Research. 2005; 33(20):e175. - Gene Definition in Different Databases and Its Implication in Microarray Data Interpretation
Pinglang Wang; Stanley J. Watson; Fan Meng
Advances in Bioinformatics and its Applications Series in Mathematical Biology and Medicine. 2005; 8:62-70. - Exploring Important Issues in The Implementation of Gene Set Enrichment Analysis
Yongjia Wang; Stanley J. Watson; Fan Meng
Advances in Bioinformatics and its Applications Series in Mathematical Biology and Medicine. 2005; 8:71-80. - Screening Potential Alllelle-Frequency Disequilibrium in Data from Affymetrix Gene Expression Arrays
Manhong Dai; Yongjia Wang; Elzbieta Sliwerska; Margit Burmeister; Stanley J. Watson; Huda Akil; Fan Meng
Advances in Bioinformatics and its Applications Series in Mathematical Biology and Medicine. 2005; 8:132-139. - A Database-Linked Diagram Editor for Biological Concepts
Bohua Yu; Manhong Dai; Stanley J. Watson; Fan Meng
Proceedings of The 2005 International Conference on Mathematics and Engineering Techniques in Medicine and Biological Sciences. 2005:281-286. - Genetical genomics: combining genetics with gene expression analysis
Jun Li; Margit Burmeister
Human Molecular Genetics. 2005; 14(2):R163-R169. - Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression
Choudary, P. V.; Molnar, M.; Evans, S. J.; Tomita, H.; Li, J. Z.; Vawter, M. P.; Myers, R. M.; Bunney,, W. E., Jr.; Akil, H.; Watson, S. J.; Jones, E. G.
PNAS. 2005; 102(43):15653-15658. - GeneInfoMiner--a web server for exploring biomedical literature using batch sequence ID
Weijian Xuan; Stanley J. Watson; Fan Meng
Bioinformatics. 2005; 21(16):3452-3453. - Suggestive linkage of schizophrenia to 5p13 in Costa Rica
K Cooper-Casey; A Me´sen-Fainardi; B Galke-Rollins; M Llach; B Laprade; C Rodriguez; S Riondet; A Bertheau; W Byerley
Molecular Psychiatry. 2005; 10(7):651-656. - Gene expression profile of G protein coupled receptor and related signaling pathways in mood disorder
H. Tomita; S. J. Evans; J. Z. Li; P. V. Choudary; M. P. Vawter; F. Meng; H. Kim; C. R. Neal; D. M. Walsh; M. E. Atz; L. Shao; R. M. Myers; E. G. Jones; S. J. Watson; H. Akil; W. E. Bunney
American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 2005; 138B(1):4-5. - Stressed and depressed.
Akil, H.
Nat Med. 2005; 11(2):116-118. - On the interactions of the hypothalamic-pituitary-adrenal (HPA) axis and sleep: normal HPA axis activity and circadian rhythm, exemplary sleep disorders
TM Buckley; AF Schatzberg
J Clin Endocrinol Metab. 2005; 90(5):3106-3114. - Aging and the role of the HPA axis and rhythm in sleep and memory-consolidation
TM Buckley; AF Schatzberg
Am J Geriatr Psychiatry. 2005; 13(5):344-352. - Mutations in squirrel monkey glucocorticoid receptor impair nuclear translocation
S. Her; P. D. Patel; A. F. Schatzberg; D. M. Lyons
J Steroid Biochem Mol Biol. 2005; 94(4):319-326. - Robust and tissue-specific expression of TPH2 versus TPH1 in rat raphe and pineal gland
Patel, Paresh D.; Pontrello, Crystal; Burke, Sharon
Biological Psychiatry. 2004; 55(4):428-433. - Dysregulation of the fibroblast growth factor system in major depression
Evans, S. J.; Choudary, P. V.; Neal, C. R.; Li, J. Z.; Vawter, M. P.; Tomita, H.; Lopez, J. F.; Thompson, R. C.; Meng, F.; Stead, J. D.; Walsh, D. M.; Myers, R. M.; Bunney, W. E.; Watson, S. J.; Jones, E. G.; Akil, H.
PNAS. 2004; 101(43):15506-15511. - Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions
Li, Jun Z.; Vawter, Marquis P.; Walsh, David M.; Tomita, Hiroaki; Evans, Simon J.; Choudary, Prabhakara V.; Lopez, Juan F.; Avelar, Abigail; Shokoohi, Vida; Chung, Tisha; Mesarwi, Omar; Jones, Edward G.; Watson, Stanley J.; Akil, Huda; Bunney, William E., Jr; Myers, Richard M.
Hum. Mol. Genet.. 2004; 13(6):609-616. - Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain
Tomita, Hiroaki; Vawter, Marquis P.; Walsh, David M.; Evans, Simon J.; Choudary, Prabhakara V.; Li, Jun; Overman, Kevin M.; Atz, Mary E.; Myers, Richard M.; Jones, Edward G.
Biological Psychiatry. 2004; 55(4):346-352. - Gender-Specific Gene Expression in Post-Mortem Human Brain: Localization to Sex Chromosomes
Vawter, Marquis P; Evans, Simon; Choudary, Prabhakara; Tomita, Hiroaki; Meador-Woodruff, Jim; Molnar, Margherita; Li, Jun; Lopez, Juan F; Myers, Rick; Cox, David; Watson, Stanley J; Akil, Huda; Jones, Edward G; Bunney; William E
Neuropsychopharmacology. 2004; 29(2):373-384. - Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional liability.
Q Wei; XY Lu; L Liu; G Schafer; KR Shieh; S Burke; TE Robinson; SJ Watson; AF Seasholtz; H Akil
Proc Natl Acad Sci. 2004; 101(32):11851-11856. - Serotonin 5-HT1A, 5-HT1B, 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia.
AL Lopez-Figueroa; CS Norton; MO Lopez-Figueroa; D Armellini-Dodel; S Burke; H Akil; JF Lopez; SJ Watson
Biol Psychiatry. 2004; 55(3):225-233. - Untangling genetic networks of panic, phobia, fear and anxiety
Villafuerte, Sandra; Burmeister, Margit
Genome Biology. 2003; 4(8):224. - Evaluation of Sensitivity, Performance and Reproducibility of Microarray Technology in Neuronal Tissue
Evans, S. J.; Watson, S. J.; Akil, H.
Integrative and Comparative Biology. 2003; 43(6):780-785. - Microarray Technology: A Review of New Strategies to Discover Candidate Vulnerability Genes in Psychiatric Disorders
Bunney, William E.; Bunney, Blynn G.; Vawter, Marquis P.; Tomita, Hiroaki; Li, Jun; Evans, Simon J.; Choudary, Prabhakara V.; Myers, Richard M.; Jones, Edward G.; Watson, Stanley J.; Akil, Huda
Am. J. Psychiatry. 2003; 160(4):657-666. - DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles
Evans, S. J.; Choudary, P. V.; Vawter, M. P.; Li, J.; Meador-Woodruff, J. H.; Lopez, J. F.; Burke, S. M.; Thompson, R. C.; Myers, R. M.; Jones, E. G.
Neurobiology of Disease. 2003; 14(2):240-250. - MRNA expression patterns and distribution of white matter neurons in dorsolateral prefrontal cortex of depressed patients differ from those in schizophrenia patients
Molnar, Margherita; Potkin, Steven G.; Bunney, Jr., William E.; Jones, Edward G.
Biological Psychiatry. 2003; 53(1):39-47. - Identifying Gene and Protein Names from Biological Texts
W. Xuan; S. J. Watson; H.Akil; F. Meng
IEEE Computer Society Bioinformatics Conference Proceedings. 2003:639-644. - Brainstem substrates of sympatho-motor circuitry identified using trans-synaptic tracing with pseudorabies virus recombinants
Kerman, I. A.; Enquist, L. W.; Watson, S. J.; Yates, B. J.
Journal of Neuroscience. 2003; 23(11):4657-66. - Mineralocorticoid receptor function in major depression.
Elizabeth A. Young; Juan F. Lopez; Virginia Murphy-Weinberg; Stanley J. Watson; Huda Akil
Arch Gen Psychiatry. 2003; 60(1):24-28. - ProbeMatchDB--a web database for finding equivalent probes across microarray platforms and species
P. Wang; F. Ding; H. Chiang; R. C. Thompson; S.J. Watson; F. Meng
Bioinformatics. 2002; 18(3):488-489. - Expression of mRNAs related to the GABAergic and glutamatergic neurotransmitter systems in the human thalamus: normal and schizophrenic
G Popken; MG Leggio; WE Bunney; EG Jones
Thalamus and Related Systems. 2002:349-369. - Hormonal evidence for altered responsiveness to social stress in major depression.
EA Young; JF Lopez; Murphy-Weinberg V; SJ Watson; H Akil
Neuropsychopharmacology. 2000; 23(4):411-418. - The "chip" as a specific genetic tool.
Stanley J. Watson; Fan Meng; Robert C. Thompson; Huda Akil
Biol Psychiatry. 2000; 48(12):1147-1156.